Cialis vs Viagra: The Battle of the Titans – Unveiling the Mechanism Behind These Potent ED Medications
Introduction
Cialis and Viagra are two popular erectile dysfunction drugs that work by increasing blood flow to the penis. While both medications have a similar mechanism of action, they differ in their onset of action, duration of effect, and side effects. In this article, we will compare and contrast Cialis and Viagra to help you make an informed decision about which drug is right for you.
Mechanism of Action
Cialis and Viagra belong to a class of drugs known as phosphodiesterase type 5 (PDE5) inhibitors. They work by inhibiting the enzyme PDE5, which is responsible for breaking down cyclic guanosine monophosphate (cGMP). By inhibiting PDE5, these drugs increase the levels of cGMP in the body, leading to relaxation of smooth muscle cells in the penis and increased blood flow.
Onset of Action
Cialis has a longer onset of action than Viagra, taking approximately 30 minutes to start working compared to 60 minutes for Viagra. However, Cialis has a longer duration of effect, lasting up to 36 hours compared to 4-6 hours for Viagra. This makes Cialis a popular choice for men who prefer spontaneity in their sexual activity.
Dosage
Both drugs come in different doses, with Cialis available in 2.5mg, 5mg, 10mg, and 20mg tablets, while Viagra is available in 25mg, 50mg, and 100mg tablets. The recommended starting dose for both drugs is typically the lowest available dose.
Efficacy
Clinical studies have shown that both Cialis and Viagra are effective at treating erectile dysfunction. However, some men may find one drug more effective than the other based on individual factors such as age, underlying health conditions, and lifestyle habits.
Side Effects
Both drugs have similar side effects, including headache, facial flushing, and nasal congestion. However, Cialis may also cause back pain and muscle aches, while Viagra may cause visual disturbances such as blue-tinted vision or sensitivity to light.
Interaction with Other Drugs
Both drugs can interact with nitrates, which are often prescribed for chest pain, and should not be taken together. In addition, both drugs can interact with alpha-blockers, which are often prescribed for high blood pressure or prostate problems.
Cialis vs Viagra for Daily Use
Cialis is also available in a lower dose (2.5mg or 5mg) for daily use. This allows men to maintain a constant level of the drug in their system, which can improve erectile function over time. Viagra is not approved for daily use.
Cialis vs Viagra for BPH
Cialis is also approved for the treatment of benign prostatic hyperplasia (BPH), a condition in which the prostate gland becomes enlarged and causes urinary symptoms. Viagra is not approved for this use.
Cialis vs Viagra Cost
Both drugs can be expensive, with Cialis typically costing more than Viagra. However, generic versions of both drugs are now available, which can significantly reduce the cost.
Conclusion
In conclusion, both Cialis and Viagra are effective treatments for erectile dysfunction that work by increasing blood flow to the penis. While they have similar mechanisms of action, they differ in their onset of action, duration of effect, and side effects. Ultimately, the choice between these drugs will depend on individual factors such as efficacy, cost, and lifestyle preferences.
References
1. Cialis (tadalafil) prescribing information. Eli Lilly and Company. 2021.
2. Viagra (sildenafil) prescribing information. Pfizer Inc. 2021.
3. Montorsi F, Padma-Nathan H, Buvat J et al. Earliest time to onset of action leading to successful intercourse with vardenafil determined in an at-home setting: a randomized, double-blind, placebo-controlled trial. J Sex Med. 2004;1(2):168-178.
4. Mulhall JP, Goldstein I, Bushmakin AG et al. Validation of the erection hardness score. J Sex Med. 2007;4(6):1626-1634.
5. Mayo Clinic. Erectile dysfunction: Viagra and other oral medications. Accessed August 23, 2021.
